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Synthèse et Activité de Quelques Hétérocycles Azotés (رقم التسجيلة. 19452)

تفاصيل مارك
100 1# - 100
a Abdelbaki, halla
245 00 - 245
a Synthèse et Activité de Quelques Hétérocycles Azotés
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b
c 2025
942 ## - 942
c THESIS
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c 19452
d 19452
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9 48494
a MAIN
b MAIN
d 2026-06-02
o TD543/011/01
p MAIN-1-17385
y THESIS
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-- Synthèse et Activité de Quelques Hétérocycles Azotés
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-- In this study, we synthesized 1,2,3-triazoles via a one-pot, multi-component reaction using Cu2O microbeads as catalysts, enhancing reaction conditions and yields (33-85%). The Cu2O microbeads were synthesized in a green environment using an aqueous extract of Artemisia campestris L., resulting in a flower-like morphology with a cubic close-packed crystal structure and a particle size of 3-6 ?m. <br/>Following triazole synthesis, we created thiosemicarbazone intermediates with moderate to good yields (32-74%) by condensing triazoles with thiosemicarbazide, allowing for thiazole derivatives formation in moderate to exceptional yields (21-86%), by their condensation with chloroacetone that expands their pharmacological applications.<br/>Finally, we evaluated the antioxidant activity of the synthesized products (triazoles, thiosemicarbazones, and thiazoles) using standard radical scavenging assays (DPPH and ABTS) to assess their therapeutic potential against oxidative stress-related diseases. These compounds exhibit significant antioxidant properties. <br/>The structures of the synthesized compounds were confirmed using 13C NMR, 1H NMR, and FTIR techniques.
650 #4 - 650
-- /Synths̈e//et//Activit/̌/de//Quelques//Hťřocycles//Azotš/
700 1# - 700
-- Djemoui, Amar

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